Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Oridonin | 28957-04-2 | 99.9% | 364.43 | 200 MG
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Oridonin is a diterpenoid isolated from *Rabdosia rubescens*. It acts as an inhibitor of AKT, with IC50s of 8.4 μM for AKT1 and 8.9 μM for AKT2. Oridonin also exhibits anti-tumor, anti-bacterial, and anti-inflammatory effects. It is intended for research use only.
- Inhibits AKT1 (IC50: 8.4 μM) and AKT2 (IC50: 8.9 μM)
- Exhibits anti-tumor effects
- Exhibits anti-bacterial effects
- Exhibits anti-inflammatory effects
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Medchemexpress LLC Cilazapril monohydrate | 92077-78-6 | 99.9% | C22H33N3O6 | 1 ML
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Cilazapril monohydrate is an orally active prodrug of the angiotensin-converting enzyme (ACE) inhibitor Cilazaprilat. It reduces plasma ACE activity and can be used in the research of hypertension (including essential and renal hypertension) and congestive heart failure. This product is for research use only and not sold to patients.
- Orally active prodrug
- Reduces plasma ACE activity
- Used in research of hypertension
- Used in research of congestive heart failure
- Evokes significant plasma ACE inhibition
- Reduces blood pressure in dogs with renal hypertension
- Improves postischemic myocardial function in hyperthyroid rats
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TARGETMOL CHEMICALS INC Repaglinide 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically apparent acute liver injury. Purity 99.66%
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TARGETMOL CHEMICALS INC Fluoxetine 200MG
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Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity. Purity 99.65%
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eMolecules Medchem Express / Mefloquine (hydrochloride) / 100mg / 446268425 / HY-17437A / / 51773-92-3 / MFCD22208579 / 414.780 / C17H17ClF6N2O
Medchem Express / Mefloquine (hydrochloride) / 100mg / 446268425 / HY-17437A / / 51773-92-3 / MFCD22208579 / 414.780 / C17H17ClF6N2O
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Medchemexpress LLC Mefloquine | 53230-10-7 | 99.96% | 378.31 | 50 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine also acts as a K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM. It can be utilized for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard of Mefloquine.
- Intended for research and analytical applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM.
- Applicable for malaria, systemic lupus erythematosus, and cancer research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
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Medchemexpress LLC Mefloquine | 53230-10-7 | 100.0% | 378.31 g·mol-1 | C17H16F6N2O | 10 MG
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Mefloquine is an orally active quinoline antimalarial agent used in biomedical research. It has reported activity as an inhibitor of SARS-CoV-2 entry and as a K+ channel antagonist (IC50 ≈1 μM). Supplied as a solid for research use only; not intended for clinical or human therapeutic use.
- High purity (HPLC 99.96%).
- Chemical formula C17H16F6N2O; molecular weight 378.31 g·mol-1.
- CAS number 53230-10-7.
- Common uses: malaria, autoimmune disease, and oncology research.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Selleck Chemical LLC Hydroquinidine S4658-100mg
Hydroquinidine (Dihydroquinidine Hydroconchinine Hydroconquinine Dihydroquinine) is an antiarrhythmic agent
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Medchemexpress LLC Hydroquinine | 1 G
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Hydroquinine | 1 G
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Medchemexpress LLC Hydroquinine | 522-66-7 | 99.84% | 326.44 | 5 G
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Hydroquinine | 522-66-7 | 99.84% | 326.44 | 5 G
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Medchemexpress LLC Quinine sulfate | 549-56-4 | 97.0% | 100 MG
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Quinine sulfate from MedChemExpress is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker with an IC50 of 19.9 μM. It is also used for malaria research.
- Acts as an antiarrhythmic agent.
- Functions as a potent, orally active, selective cytochrome P450db inhibitor.
- Blocks K+ channels with an IC50 of 19.9 μM.
- Suitable for malaria research.
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Medchemexpress LLC Quinine | 130-95-0 | 25 G
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Quinine is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent and a potassium channel inhibitor. It inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
- Derived from cinchona tree bark
- Acts as an anti-malaria agent
- Functions as a potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
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Medchemexpress LLC Quinine hydrochloride | 130-89-2 | 99.8% | 360.88 | 10 MG
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Quinine hydrochloride is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent and potassium channel inhibitor. It inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV.
- Acts as an anti-malaria agent.
- Functions as a potassium channel inhibitor.
- Inhibits WT mouse Slo3 (KCa5.1) channel currents.
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Apexbio Technology LLC Mefloquine hydrochloride 51773-92-3 10mM (in 1mL DMSO)
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Mefloquine hydrochloride is a quinoline-based antimalarial compound structurally related to quinidine with demonstrated inhibitory effects on Plasmodium falciparum It functions primarily through modulation of potassium ion channels displaying an IC50 around 1 M against KvLQT1/minK channel currents and approximately 5 6 M against HERG channel currents Research indicates that mefloquine induces cellular oxidative stress modulating intracellular signaling pathways including Akt phosphorylation ERK JNK and AMPK in vitro Current studies also explore its potential cytotoxic activity toward cancer cell lines and evaluate effectiveness against urinary schistosomiasis in phase 2 clinical trials
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